Deep wrinkles, furrows and expression lines can be treated with a variety of injectable agents. These include Restylane, Perlane, Juvederm, Teosyal, Evolence, Revanesse and Radiesse. These treatments consist of hyaluronic acid injections. The effects last from 6 – 9 months or up to 2 years with Radiesse. Patients may notice some swelling and bruising after treatment for a few days.